GrippeBresilV1, Main, Exploration, bibRecord, 000066

Effects of extracts from Echinacea purpurea (L) MOENCH on mice infected with different strains of Toxoplasma gondii.

Identifieur interne : 000066 ( Main/Exploration ); précédent : 000065; suivant : 000067

Effects of extracts from Echinacea purpurea (L) MOENCH on mice infected with different strains of Toxoplasma gondii.

Auteurs : Arquimedes Gasparotto Junior [Brésil] ; Maria Luiza Antonio Cosmo [Brésil] ; Michelle De Paula Reis [Brésil] ; Pamela Secundo Dos Santos [Brésil] ; Daniela Dib Gonçalves [Brésil] ; Francielly Mourão Gasparotto [Brésil] ; Italmar Teodorico Navarro [Brésil] ; Emerson Luiz Botelho Lourenço [Brésil]

Source :

Parasitology research [ 1432-1955 ] ; 2016.

RBID : pubmed:27277433

Descripteurs français

KwdFr :
- Animaux, Brésil, Echinacea (), Extraits de plantes (isolement et purification), Extraits de plantes (pharmacologie), Fleurs (), Foie (parasitologie), Immunomodulation, Liquide d'ascite (parasitologie), Modèles animaux de maladie humaine, Mâle, Souris, Toxoplasma (), Toxoplasmose (traitement médicamenteux).
MESH :
- isolement et purification : Extraits de plantes.
- parasitologie : Foie, Liquide d'ascite.
- pharmacologie : Extraits de plantes.
- traitement médicamenteux : Toxoplasmose.
- Animaux, Brésil, Echinacea, Fleurs, Immunomodulation, Modèles animaux de maladie humaine, Mâle, Souris, Toxoplasma.

English descriptors

KwdEn :
- Animals, Ascitic Fluid (parasitology), Brazil, Disease Models, Animal, Echinacea (chemistry), Flowers (chemistry), Immunomodulation, Liver (parasitology), Male, Mice, Plant Extracts (isolation & purification), Plant Extracts (pharmacology), Toxoplasma (drug effects), Toxoplasmosis (drug therapy).
MESH :
- chemical , isolation & purification : Plant Extracts.
- chemistry : Echinacea, Flowers.
- drug effects : Toxoplasma.
- drug therapy : Toxoplasmosis.
- parasitology : Ascitic Fluid, Liver.
- chemical , pharmacology : Plant Extracts.
- Animals, Brazil, Disease Models, Animal, Immunomodulation, Male, Mice.

Abstract

In recent years, due to the growing concern about recurrent epidemics by Toxoplasma gondii and other pathogens in Brazil, there has been an increase in the use of different preparations obtained from Echinacea purpurea in order to test their effectiveness against these infections. Although studies have suggested the beneficial effects of this species against the influenza virus, no data are available on the use of E. purpurea aqueous extract in T. gondii infections. Thus, the aim of this study was to analyze the effect of its administration in Swiss mice submitted to acute and prolonged infection with different T. gondii strains. This study showed that E. purpurea extract induced a significant reduction in the number of tachyzoites in the peritoneal fluid and liver imprints from mice infected by the RH strain. Moreover, prolonged treatment significantly increased the number of brain cysts of animals infected with ME 49 strain. The results obtained in this study suggest that the crude extract obtained from E. purpurea has important protective activities against infection with different T. gondii strains.

DOI: 10.1007/s00436-016-5167-2
PubMed: 27277433

Affiliations:

Links toward previous steps (curation, corpus...)

to stream Main, to step Corpus: 000081
to stream Main, to step Curation: 000081

Le document en format XML

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<term>Extraits de plantes (pharmacologie)</term>
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<term>Immunomodulation</term>
<term>Liquide d'ascite (parasitologie)</term>
<term>Modèles animaux de maladie humaine</term>
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<front><div type="abstract" xml:lang="en">In recent years, due to the growing concern about recurrent epidemics by Toxoplasma gondii and other pathogens in Brazil, there has been an increase in the use of different preparations obtained from Echinacea purpurea in order to test their effectiveness against these infections. Although studies have suggested the beneficial effects of this species against the influenza virus, no data are available on the use of E. purpurea aqueous extract in T. gondii infections. Thus, the aim of this study was to analyze the effect of its administration in Swiss mice submitted to acute and prolonged infection with different T. gondii strains. This study showed that E. purpurea extract induced a significant reduction in the number of tachyzoites in the peritoneal fluid and liver imprints from mice infected by the RH strain. Moreover, prolonged treatment significantly increased the number of brain cysts of animals infected with ME 49 strain. The results obtained in this study suggest that the crude extract obtained from E. purpurea has important protective activities against infection with different T. gondii strains. </div>
</front>
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<Abstract><AbstractText>In recent years, due to the growing concern about recurrent epidemics by Toxoplasma gondii and other pathogens in Brazil, there has been an increase in the use of different preparations obtained from Echinacea purpurea in order to test their effectiveness against these infections. Although studies have suggested the beneficial effects of this species against the influenza virus, no data are available on the use of E. purpurea aqueous extract in T. gondii infections. Thus, the aim of this study was to analyze the effect of its administration in Swiss mice submitted to acute and prolonged infection with different T. gondii strains. This study showed that E. purpurea extract induced a significant reduction in the number of tachyzoites in the peritoneal fluid and liver imprints from mice infected by the RH strain. Moreover, prolonged treatment significantly increased the number of brain cysts of animals infected with ME 49 strain. The results obtained in this study suggest that the crude extract obtained from E. purpurea has important protective activities against infection with different T. gondii strains. </AbstractText>
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<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Gasparotto Junior</LastName>
<ForeName>Arquimedes</ForeName>
<Initials>A</Initials>
<AffiliationInfo><Affiliation>Laboratory of Electrophysiology and Cardiovascular Pharmacology, Faculty of Health Sciences, Federal University of Grande Dourados, Rodovia Dourados-Itahum, km 12, P.O. Box 533, 79.804-970, Dourados, MS, Brazil. arquimedesgasparotto@gmail.com.</Affiliation>
</AffiliationInfo>
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<Author ValidYN="Y"><LastName>Cosmo</LastName>
<ForeName>Maria Luiza Antonio</ForeName>
<Initials>ML</Initials>
<AffiliationInfo><Affiliation>Laboratory of Pharmacology and Toxicology of Natural Products, Universidade Paranaense, Umuarama, PR, Brazil.</Affiliation>
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<Author ValidYN="Y"><LastName>Reis</LastName>
<ForeName>Michelle de Paula</ForeName>
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<AffiliationInfo><Affiliation>Laboratory of Pharmacology and Toxicology of Natural Products, Universidade Paranaense, Umuarama, PR, Brazil.</Affiliation>
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<ForeName>Daniela Dib</ForeName>
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<AffiliationInfo><Affiliation>Laboratory of Pharmacology and Toxicology of Natural Products, Universidade Paranaense, Umuarama, PR, Brazil.</Affiliation>
</AffiliationInfo>
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<Author ValidYN="Y"><LastName>Gasparotto</LastName>
<ForeName>Francielly Mourão</ForeName>
<Initials>FM</Initials>
<AffiliationInfo><Affiliation>Laboratory of Electrophysiology and Cardiovascular Pharmacology, Faculty of Health Sciences, Federal University of Grande Dourados, Rodovia Dourados-Itahum, km 12, P.O. Box 533, 79.804-970, Dourados, MS, Brazil.</Affiliation>
</AffiliationInfo>
</Author>
<Author ValidYN="Y"><LastName>Navarro</LastName>
<ForeName>Italmar Teodorico</ForeName>
<Initials>IT</Initials>
<AffiliationInfo><Affiliation>Animal Science Department, Londrina State University, Londrina, PR, Brazil.</Affiliation>
</AffiliationInfo>
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<Author ValidYN="Y"><LastName>Lourenço</LastName>
<ForeName>Emerson Luiz Botelho</ForeName>
<Initials>EL</Initials>
<AffiliationInfo><Affiliation>Laboratory of Pharmacology and Toxicology of Natural Products, Universidade Paranaense, Umuarama, PR, Brazil.</Affiliation>
</AffiliationInfo>
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</ArticleIdList>
<ReferenceList><Reference><Citation>Anal Bioanal Chem. 2010 Jun;397(3):1259-71</Citation>
<ArticleIdList><ArticleId IdType="pubmed">20349350</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Vaccine. 2010 May 21;28(23):3956-62</Citation>
<ArticleIdList><ArticleId IdType="pubmed">20382242</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Bioorg Med Chem Lett. 2015 Aug 15;25(16):3091-4</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26105195</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Int J Antimicrob Agents. 2008 Oct;32(4):360-2</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18619816</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Infect Dev Ctries. 2016 Jan 31;10 (1):13-23</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26829533</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Antimicrob Agents Chemother. 1995 Oct;39(10):2371-2</Citation>
<ArticleIdList><ArticleId IdType="pubmed">8619602</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Talanta. 2005 Jun 15;66(5):1094-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18970094</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Microbes Infect. 2015 Aug;17(8):586-95</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25899946</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Ethnopharmacol. 2015 Apr 22;164:136-46</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25680844</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Clin Infect Dis. 2008 Jun 1;46 Suppl 5:S378-85</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18462093</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Int J Parasitol. 2004 Mar 9;34(3):411-21</Citation>
<ArticleIdList><ArticleId IdType="pubmed">15003500</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Pharmacogn Rev. 2015 Jan-Jun;9(17):63-72</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26009695</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Front Microbiol. 2014 Oct 13;5:492</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25352834</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Parasitology. 2012 Sep;139(11):1375-424</Citation>
<ArticleIdList><ArticleId IdType="pubmed">22776427</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Trends Microbiol. 2008 Aug;16(8):361-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18585915</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Virol J. 2009 Nov 13;6:197</Citation>
<ArticleIdList><ArticleId IdType="pubmed">19912623</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Cell Immunol. 2015 Oct;297(2):94-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26190752</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Biomed Biotechnol. 2012;2012:769896</Citation>
<ArticleIdList><ArticleId IdType="pubmed">22131823</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Parasitol Res. 2011 Jul;109(1):133-8</Citation>
<ArticleIdList><ArticleId IdType="pubmed">21207062</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Pharmacol Ther. 1990;48(1):45-59</Citation>
<ArticleIdList><ArticleId IdType="pubmed">2274577</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>PLoS One. 2015 May 01;10(5):e0124276</Citation>
<ArticleIdList><ArticleId IdType="pubmed">25933416</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Antimicrob Agents Chemother. 2001 Apr;45(4):1271-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">11257045</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Ethnopharmacol. 2008 Aug 13;118(3):503-7</Citation>
<ArticleIdList><ArticleId IdType="pubmed">18602775</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Arch Ophthalmol. 1959 Oct;62:611-5</Citation>
<ArticleIdList><ArticleId IdType="pubmed">14404853</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>J Biol Chem. 1998 Feb 6;273(6):3461-9</Citation>
<ArticleIdList><ArticleId IdType="pubmed">9452469</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Curr Ther Res Clin Exp. 2015 Apr 20;77:66-72</Citation>
<ArticleIdList><ArticleId IdType="pubmed">26265958</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Schizophr Bull. 2007 May;33(3):745-51</Citation>
<ArticleIdList><ArticleId IdType="pubmed">17322557</ArticleId>
</ArticleIdList>
</Reference>
<Reference><Citation>Pharm Biol. 2010 Sep;48(9):1047-52</Citation>
<ArticleIdList><ArticleId IdType="pubmed">20731557</ArticleId>
</ArticleIdList>
</Reference>
</ReferenceList>
</PubmedData>
</pubmed>
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Effects of extracts from Echinacea purpurea (L) MOENCH on mice infected with different strains of Toxoplasma gondii.

Effects of extracts from Echinacea purpurea (L) MOENCH on mice infected with different strains of Toxoplasma gondii.

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